Camptothecin is the active agent derived from the bark extract of the Camptotheca acuminata tree. Two analogs of camptothecin have been developed that are clinically active and less toxic than the parent compound: irinotecan (CPT-11) and topotecan (see Figs. 2.12A,B) [161].Both the agents are under investigation for efficacy against solid tumors, including PBT and MBT.

Camptotheca (happy tree, cancer tree, or tree of life) is a genus of medium-sized deciduous trees growing to 20 metres (66 ft) tall, native to southern China and Tibet. The genus is usually included in the tupelo family Nyssaceae, but sometimes included (with the tupelos) in the dogwood family Cornaceae.. The name "happy tree" is a direct translation of the Chinese name xǐ shù (Simplified ...

Camptothecin (CPT) is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native to China.

Certification: ISO, FDA, Kosher Assay Method: HPLC Application: Medicine State: Crystal Extract Source: Camptotheca Acuminata Decne Botanical Source: Nothapodytes Pittosporoides (Oliv.) Sleum

Currently in China, no technically and economically viable methods exist to handle large quantities of Camptotheca acuminata Decne residue (CA residue) after camptothecin extract while there is a ...

Camptotheca acuminata Decne. Camptotheca acuminata es un árbol perteneciente a la familia de las cornáceas, caducifolio, de tamaño medio que alcanza los 20 m de altura. Es nativo de China central y del Tíbet. Es utilizado como planta medicinal en el tratamiento del cáncer. [1] Frutos. Vista de la planta ...

Camptotheca acuminata Decne: 98% Down: 35: Capsaicinoids : Red Chilli Extract: 95% Down: 36: 's Claw P.E. Ranunculus ternatus Thunb: Total Alkaloids 3% Down: 37: Centella asiatica Extract : Centella asiatica (L.) Urb. Asiaticoside 10% Down: 38: Cephalomannine: Taxus Chinese: 98% Down: 39: Chamomile Extract: Matricaria Recutita: Apigenin 1%/2 ...

Currently in China, no technically and economically viable methods exist to handle large quantities of Camptotheca acuminata Decne residue (CA residue) after camptothecin extract while there is a great demand for low cost alternatives to replace the cottonseed hull-based materials used in commercial mushroom culture. Hence, it is of importance for camptothecin extract factories and …

Camptotheca acuminata Decne. Xishu: Chinese Mosla Herb: Herba Moslae: Xiangru: Ciliatenerve Knotweed Root: Radix Polygoni Ciliinerve: Zhushalian: Chinese goldthread rhizome: ... Natural Sophora root extract 20: 1 quality assurance/Bitter Sophora Root Extract Contact Now. Pomegranate Peel polyphenol Pomegranate Peel Extract Powder Contact ...

As Camptotheca acuminata Decne. The World Checklist of Vascular Plants (WCVP) As Camptotheca acuminata Decne. Integrated Taxonomic Information System (ITIS) As Camptotheca acuminata Decne. Catalogue of Life China, 2013 Annual Checklist (Biodiversity Committee, Chinese Academy of Sciences) As Camptotheca acuminata Decne.

Camptotheca acuminata Decne (Fam. ‐ Nyssaceae) is a deciduous tree endemic to China, and its bark and fruits have been used in folk medicine to treat cancer virus and and bacterial diseases.

Camptotheca Acuminata Decne Extract Irinotecan Hydrochloride USP41 Powder Function : 1 It is the first medicine that is used for treating the metastatic colon rectum cancer; it also has very good effects to non...

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Camptotheca acuminata Decne extract 98% Camptothecin by HPLC Shanghai Cormorana International Trading Co., Ltd. 1 Kilogram (Min. Order) Our businesses have already extended to more than 50 countries that separately located in Europe, America, East & Southeast Asia, Africa and Oceania., Ltd is an innovative company which is delicated in ...

Camptothecin is the active agent derived from the bark extract of the Camptotheca acuminata tree. Two analogs of camptothecin have been developed that are clinically active and less toxic than the parent compound: irinotecan (CPT-11) and topotecan (see Figs. 2.12A,B) [161].Both the agents are under investigation for efficacy against solid tumors, including PBT and MBT.

The Chinese happy tree, Camptotheca acuminata Decne, is grown extensively in plantations for harvest and extraction of its anti-cancer and potentially anti-viral compound, camptothecin. This study determined whether C. acuminata was amenable to clonal propagation as rooted cuttings and whether application of the rooting hormone, indole-3 ...

Camptotheca Acuminata Extract/Camptothecin of 98% 10-Hydroxycamptothecin Camptothecin (CPT), Find Details about Camptotheca Acuminata Decne Extract, Nothapodytes Pittosporoides (Oliv.) Sleum from Camptotheca Acuminata Extract/Camptothecin of 98% 10-Hydroxycamptothecin Camptothecin (CPT) - Xi'an Qingshuo Import and Export Trade Co., Ltd.

Camptotheca acuminata Decaisne (Nyssaceae) is a deciduous tree native to south China and Tibet, where it is known as "Xi Shu" or "Happy Tree".C. acuminata is a main natural source of the terpenoid indole alkaloid (TIA) camptothecin (CPT), which was first isolated in 1966 by Wall and coworkers [].CPT has received great attention for its remarkable antitumor activities, which result from …

Camptotheca Acuminata Decne Extract Irinotecan Hydrochloride USP41 Powder . Function : 1 It is the first medicine that is used for treating the metastatic colon rectum cancer; it also has very good effects to non- small-cell carcinoma of the lung and small-cell carcinoma of the lung.

Camptothecin is a quinoline-based alkaloid found in the barks of the chinese camptotheca tree and the Asian nothapodytes tree. Features. CAS No. Specification: 98%,99% Camptothecin Test method: HPLC Appearance: Light yellow crystal powder Source: Camptotheca Acuminata Decne…

Ultrasonic Assisted-Reflux Synergistic Extraction of Camptothecin and Betulinic Acid from Camptotheca acuminata Decne. Fruits. (PMID:28654014 PMCID:PMC6152106) ... methods have been combined in the UARSE method and used to extract CPT and BA for the first time. ... method for extracting CPT and BA from the fruits of C. acuminata Decne.

Published date: Oct 17, 2018 Tags: Camptothecin Camptotheca acuminata Camptothecin is an alkaloid derived from the Chinese tree Camptotheca acuminata Decne. Camptotheca acuminata extract and its derivatives are unique in their ability to inhibit DNA Topoisomerase I, by stabilizing a covalent reaction intermediate termed the cleavable complex which …

The bark and stems of Camptotheca acuminata contain the alkaloid camptothecin. Several chemical derivatives of camptothecin are under investigation for or used as drugs for cancer treatment, including irinotecan, topotecan, rubitecan. Camptotheca acuminata also contains the chemical compounds trifolin and hyperoside.

Camptothecin is a potent natural product based anticancer agent isolated from an organic extract of the bark of a Chinese tree, Camptotheca acuminata, Decaisne (Nyssaceae). The chemical identification of camptothecin was first reported in 1966 by Wall et al (1) as a plant alkaloid which showed strong potency against a number of cancer cells ...

Camptotheca acuminata Decne residue after camptothecin extract as a substrate to produce mushroom spawn. Journal of Mountain Science, 2012, 9(6):835-841. DOI: 10.1007/s11629-012-2553-9. Professional Membership

Camptothecins, a kind of monoterpene-quinoline alkaloids from Camptotheca acuminata Decne, have long attracted much attention worldwide as an anti-cancer drug. However, there is still a lack of effective methods for the accumulation and discovery of camptothecin analogues from botanic resources for camptothecin-based drug research.

Camptothecin is extracted from Camptotheca acuminata Decne. Stanford Chemicals has been providing quality Camptothecin and many other natural plant extract for over 15 years. Product Name: Camptothecin. CAS No. . Molecular Formula: C 20 H 16 N 2 O 4: Molecular Weight: 348.34. Botanical Source: Camptotheca acuminata Decne:

Camptothecin (CPT), a natural alkaloid isolated from Camptotheca acuminata Decne, is found to show potential insecticidal activities with unique action …

Camptotheca acuminata Decne (Nyssaceae) human colon HCT116, breast cancer cells (MCF-7), prostate cancer (DU145), leukaemia (CEM) IC 50 of CPT: HCT116 169.5 nmol/L MCF-7 180.3 nmol/L DU145 15,700 nmol/L CEM 13,600 nmol/L: binds to a complex consisting of DNA and topoisomerase I stabilises the topoisomerase I () complex and the ruptured DNA

for extracting camptothecin (CPT) and betulinic acid (BA) from Camptotheca acuminata Decne. fruits has been developed in this study. The advantages of the ultrasonic and reflux extraction methods have been combined in the UARSE method and used to extract CPT and BA for the first time.

campothecin derivatives, isolated from Camptotheca acuminata Decne (Nyssaceae). The C. acuminate extract has shown an effective anti-tumor activity. Extensive investigations are still in pursuit in search of more effective camptothecin derivative. Certain compounds such as Topotecan- developed

A novel and efficient ultrasonic assisted-reflux synergistic extraction (UARSE) method for extracting camptothecin (CPT) and betulinic acid (BA) from Camptotheca acuminata Decne. fruits has been developed in this study. The advantages of the ultrasonic and reflux extraction methods have been combined in the UARSE method and used to extract CPT and BA for the first time.

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Camptotheca Acuminata Decne. Trademark. KINGHERBS _ KH. Transport Package. 25kg/Drum. Specification. ISO 9001. KOSHER CERTIFICATE ... Customer Question & Answer Ask something for more details KINGHERBS' Camptothecine . CAS#: . Other Names: Camptotheca Acuminata Extract, Nothapodytes pittosporoides extract. Botanical Source ...

A novel and efficient ultrasonic assisted-reflux synergistic extraction (UARSE) method for extracting camptothecin (CPT) and betulinic acid (BA) from Camptotheca acuminata Decne. fruits has been developed in this study. The advantages of the ultrasonic and reflux extraction methods have been combined in the UARSE method and used to extract CPT and BA for the first time.

Camptothecin, a widely used natural anti‐cancer drug, is difficult to extract and purify effectively from plants. Objective. To develop new and highly efficient extraction and purification methods for analysis and production of camptothecin from leaves and fruits of Camptotheca acuminata and Nothapodytes pittosporoides roots. Methods

Anti-Cancer Camptotheca Extract Camptothecin Brief Information of Camptotheca Extract Camptothecin: Product Name: Camptotheca Extract Camptothecin Botanical Source: Camptotheca acuminata Decne Part Used: Fruit & Leaf Ingredient: Camptothecin Appearance: Light Yellow Crystalline Specs: 92%, 95%, 98% Test Method: HPLC Cas No.